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Hilla University College Journal For Medical Science

Corresponding Author

Zahraa M. Altaee

Document Type

Review

Keywords

Staphylococcal scalded skin (SSS) syndrome, S. aureus, Exfoliative toxins (ETs)

Abstract

Staphylococcal scalded skin syndrome (SSSS) is a skin problem characterized by the formation of blisters. It primarily affects newborns, young children, and adults with pre-existing medical conditions. This condition is caused by an infection from the bacteria Staphylococcus aureus. The cause of this case is the breakdown of desmoglein-1, a protein in the skin, due to the action of exotoxins. This results in the outer layer of the skin's cells peeling off. The SSSS is caused by the dissemination of toxins throughout the body, leading to a widespread rash and a severe manifestation of symptoms. Staphylococcal scalded skin syndrome manifests as the formation of blisters on the outermost layers of the skin, caused by the release of exfoliative toxins from S. aureus. Erythematous cellulitis develops with the rapid exfoliation of skin cells. A sign of SSSS is a small number of blisters restricted to the infection site that progress to widespread exfoliation that affects the entire body. The condition is managed using antibiotics that specifically target S. aureus. This illness may occasionally be mistaken for other conditions that cause superficial blistering.

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