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Hilla University College Journal For Medical Science

Corresponding Author

Abdel-Raheem M. A.

Authors ORCID

Abdel-Raheem M. A.: https://orcid.org/0000-0001-9240-064X

Document Type

Original Study

Keywords

Coronavirus, Biomarkers, Viral infections, Statistical analysis, Trace elements

Abstract

Background: Coronavirus infection has been the severest pandemic in recent years. Several biomarkers for direct assessment and rapid diagnosis have been used, such as IgM and PCR.

Objectives: The aim of this study was to investigate the critical biomarkers, either a mineral or an enzymatic inhibition or activation.

Materials and Methods: This study was conducted on COVID-19 patients who were suspected of being infected with the coronavirus, using serum of 25–80 years of age, males. The following biochemical tests (LDH, CK-MB, Ferritin, Mg, Zn, Cu and Ceruloplasmin) were measured at a private laboratory in Baghdad.

Results: The results showed that three trace elements significantly changed, positively or negatively, in 50 male patients who had a severe coronavirus infection. The study explored the correlation between the above parameters and the immune system which impaired the function of some organs in the body.

Conclusion: We can conclude that all the biomarkers, including Mg, Zn, Cu, CP, CKD, LDH and ferritin, significantly changed during coronaviruses infections which are involved in the main cellular functions and play a vital role against viral infection. Our results highly recommend following these parameters clinically as biomarkers for coronavirus infection instead of performing several other viral tests.

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