The Effect of Flaxseed Oil on Fertility

Authors

• Mohammad F. Albadran, Nephrology and transplantation center, Basrah health directorate, Basrah, IraqFollow
• Ahmed B. Abdulwahid, Department of Physiology /Al-Zahraa College of Medicine, University of Basrah, Basrah, IraqFollow
• Assad H. Eissa, Department of Veterinary Public Health, Veterinary Medicine College, University of Basrah, Basrah, IraqFollow
• Nehaya M. Al-Aubody, Department of Physiology /Al-Zahraa College of Medicine, University of Basrah, Basrah, IraqFollow
• Shaymaa F. Abbas, Department of pharmacology /Al-Zahraa College of Medicine, University of Basrah, Basrah, IraqFollow
• Zainab M. Mohammed, Department of biochemistry /Al-Zahraa College of Medicine, University of Basrah, Basrah, Iraq

Corresponding Author

Ahmed B. Abdulwahid

Authors ORCID

Ahmed B. Abdulwahid: https://orcid.org/0000-0002-1174-9696

Assad H. Eissa: https://orcid.org/0000-0001-5283-8102

Nehaya M. Al-Aubody: https://orcid.org/0000-0002-0923-6541

Shaymaa F. Abbas: https://orcid.org/0000-0001-5295-0663

Zainab M. Mohammed: https://orcid.org/0000-0002-6531-6634

Document Type

Original Study

Keywords

Fertility, Infertility, Sperm count, Pregnancy, Flaxseed oil

Abstract

Background: Infertility can be defined as the inability to conceive pregnancy when sexually active and not having used any contraception in 12 months. Flaxseed oil has wide-spectrum applications in health. It has been receiving special interest in infertility treatment.

Objectives: This research aimed to determine the impact of flaxseed oil on the fertility of mice.

Methods: It involved seventy-five mice. These mice were sex-separated and randomly classified into three groups; one group served as a control group, and the other two groups were exposed to flaxseed oil extract at a dose of 60 mg/Kg body weight/day or 120 mg/Kg body weight/day for 2 weeks. The animals were redistributed at the end of the treatment period, whereby each female group was exposed to male mice from the three male groups for four weeks to investigate reproductive efficiency by calculating the pregnancy rate among females. In males, sperm count was performed with histopathological examination of the testes and epididymis.

Results: No pregnancies occurred in the flaxseed oil-treated groups, and azoospermia was observed in all the treated male groups, with marked histological alterations in the testes and epididymis.

Conclusion: Flaxseed oil had a negative influence on reproduction in both male and female mice in terms of pregnancy percentage, sperm count, with histological changes in the testis and epididymis.

How to Cite This Article

Albadran, Mohammad F.; Abdulwahid, Ahmed B.; Eissa, Assad H.; Al-Aubody, Nehaya M.; Abbas, Shaymaa F.; and Mohammed, Zainab M. (2026) "The Effect of Flaxseed Oil on Fertility," Hilla University College Journal For Medical Science: Vol. 4: Iss. 2, Article 2.
DOI: https://doi.org/10.62445/2958-4515.1108

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.